I have a clear and logical mind with a practical approach to problem-solving and a drive to see things through to completion. I enjoy working on my own initiative or in a team. In short, I am reliable, I have a strong appetite for learning and a genuine interest to do research in general, but also focused in the understanding of the positive and deleterious effects of free radicals in life but more specifically related to human degenerative diseases.
My actual research nowadays includes the role of electron transfer systems in disease. Some other areas of interest also included in my next five years of research strategic plan are associated with the study of naturally occurring compounds as potential therapeutical agents against diseases. It is a priority in future researches to identify and have a better understanding of the mechanisms controlling the enzymes that generate reactive oxygen species, since they become key mediators in the development of pathophysiological conditions, cancer and aging.
My early and late publications directly addressed the study of the NADH dependent redox systems present at the neuronal plasma membrane and its role in neuronal cell death. Both cytochrome b5 reductase and cytochrome b5 have been shown as prominent components of the so-called “plasma membrane redox chain” as pro-apoptosis markers in cerebellar granule neurons. This early research was strongly devoted to this system with the aim to unveil the circumstances under which the electron shuttle uncouples, leading to a burst of reactive oxygen species, a precondition that is in general associated with neurodegeneration.
Research Activities - Keywords
I have expertise in a multitude of biophysical and spectroscopic techniques (UV-vis, Raman, Fluorescence, CD and NMR).
Full publications list can be found at ORCiD.
Molecules, MDPI (years 2019- up to date) IMPACT FACTOR 2018: 3.060. RANKS 2018: "Physical and Theoretical Chemistry" Q2, "Pharmaceutical Science" 2018 Q1, "Organic Chemistry" Q2, "Medicine (miscellaneous)" Q2, "Drug Discovery" Q2, "Chemistry (miscellaneous)" Q1, "Analytical Chemistry" Q2